A six-story building collapsed on Syria Street, west of Shubra al-Kheima district, on Wednesday evening.
There were no reported deaths resulting from the collapse, with all residents evacuating shortly before the building came down.
Investigators say that the building was already condemned due to a lack of concrete pillars and was due for demolition.
However, they did not say what exactly sparked the collapse on Wednesday night.
Qalyubia Governor Reda Farahat headed to the scene when he heard the news and asked for a thorough investigation. He was accompanied by Alaa al-Nady, head of the district, and Mostafa Abbas, the governor's deputy secretary general.
The governor also insisted that a proper clean-up operation was started to remove the remains of the building and clean up the area.
Unsafe buildings often collapse across Egypt, with occasional deaths and injuries. In some cases, the buildings were already vacated or at least earmarked for demolition, although others simply collapse unexpectedly due to poor construction or heavy rain.
In March, several people were killed and injured when a five-storey building collapsed in Ismailia. Heavy rain was given as a possible reason for the final collapse of the unsound structure.
The same month, three buildings collapsed in the Karmouz neighborhood of Alexandria, with no deaths of injuries. The buildings, which had already been evacuated ahead of demolition, were cordoned off.
Edited translation from Al-Masry Al-Youm