The Egyptian Football Association said on Thursday the final cup match between Zamalek and Wadi Degla will go ahead without fans in the stadium.
The game will take place at Gouna stadium on Saturday.
The announcement follows a letter from the Interior Ministry, sent to EFA officials, advising that the game could go ahead providing fans were not in the stands.
Zamalek had expressed its objection to holding the game without spectators, after the Red Sea Security Directorate rejected their attendance on Wednesday.
Zamalek club chief Kamal Darwish said that the club's administration has made attempts to convince the Football Association to allow the fans to attend, but in vain.
Zamalek's hardcore fanbase, the Ultras White Knights, have declared their intention to attend the game in Gouna, despite the ban.
Egyptian authorities have been banning spectators from attending football competitions since the Port Said massacre in February 2012, in which 72 Ahly fans, most of whom were members of the Ultras Ahlawy, were violently killed after a match between Ahly and Port Said's home club, al-Masry.
Edited translation from Al-Masry Al-Youm