The U.S. embassy in Cairo said it will close on Sunday amid fears of violence at opposition protests against President Mohamed Morsy.
The embassy added that it would follow events before deciding on its work schedule next week.
The embassy also offered warnings to American nationals living in the Egyptian capital.
“As potentially violent protest activity may occur before [30 June], U.S. citizens are advised to maintain a low profile and restrict movement to the immediate area of their residences and neighborhoods starting on 28 June,” a statement said.
It also referred to reports stating opposition activists from the Tamarod ("rebel") campaign would be collecting signatures outside 16 Metro stops across Cairo on 25 June.
The embassy advised citizens to take alternative transportation.
Tamarod campaigners are continuing to collect signatures for their petition demanding early presidential elections in Egypt.